Autophagy: Press and Push for Destruction

Recent publications illustrate an extensive crosstalk between the actin cytoskeleton and autophagy, a program for self-digestion. Actin polymerization provides a pushing force for organelle shaping and trafficking during autophagy, but the cytoskeleton is also targeted by autophagy under mechanical...

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Veröffentlicht in:Current biology 2016-08, Vol.26 (15), p.R703-R705
1. Verfasser: Höhfeld, Jörg
Format: Artikel
Sprache:eng
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Zusammenfassung:Recent publications illustrate an extensive crosstalk between the actin cytoskeleton and autophagy, a program for self-digestion. Actin polymerization provides a pushing force for organelle shaping and trafficking during autophagy, but the cytoskeleton is also targeted by autophagy under mechanical strain. Recent publications illustrate an extensive crosstalk between the actin cytoskeleton and autophagy, a program for self-digestion. Actin polymerization provides a pushing force for organelle shaping and trafficking during autophagy, but the cytoskeleton is also targeted by autophagy under mechanical strain.
ISSN:0960-9822
1879-0445
DOI:10.1016/j.cub.2016.06.017