An experimental study on the comparison of the effects of triester glycerol oxide on wound repair

Aim The aim of this study is to assess the effects of triester glycerol oxide (TGO) on cutaneous wound epithelization process. Material and methods Fifty-four male Wistar rats were divided into 2 groups of 27 rats each: control(C) and TGO (PX). The groups have been divided into three subgroups which...

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Veröffentlicht in:Oral and maxillofacial surgery 2016-09, Vol.20 (3), p.273-279
Hauptverfasser: Sezgin, Serhat, Sencimen, Metin, Gülses, Aydin, Erdemci, Fevzi, Ayna, Mustafa, Gider, İsmail K., Ongoru, Onder, Cayci, Tuncer
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Sprache:eng
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Zusammenfassung:Aim The aim of this study is to assess the effects of triester glycerol oxide (TGO) on cutaneous wound epithelization process. Material and methods Fifty-four male Wistar rats were divided into 2 groups of 27 rats each: control(C) and TGO (PX). The groups have been divided into three subgroups which included nine rats each regarding the wound excision on the 3rd, 7th, and 10th days, respectively. The specimens were evaluated according to histological properties and hydroxyproline levels. Results Seventh day examination showed that PX and control groups present the same score. HP levels in the control group were significantly lower compared to PX groups. Conclusion TGO have positive effects on wound epithelization process by increased collagen synthesis.
ISSN:1865-1550
1865-1569
DOI:10.1007/s10006-016-0566-1