Recent advances in metal catalyzed intramolecular aryl additions—accessing bioactive molecules
[Display omitted] 1-Aminotetraline, 1-aminoindane, and benzocycloalkanol structures are privileged scaffolds demonstrating broad ranging pharmacological properties. In this review recent advances in the synthesis of molecules containing these scaffolds via metal catalyzed intramolecular aryl additio...
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Veröffentlicht in: | Tetrahedron letters 2016-03, Vol.57 (11), p.1197-1204 |
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Format: | Artikel |
Sprache: | eng |
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Online-Zugang: | Volltext |
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Zusammenfassung: | [Display omitted]
1-Aminotetraline, 1-aminoindane, and benzocycloalkanol structures are privileged scaffolds demonstrating broad ranging pharmacological properties. In this review recent advances in the synthesis of molecules containing these scaffolds via metal catalyzed intramolecular aryl additions to activated groups like: imines, ketones, and aldehydes are discussed. |
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ISSN: | 0040-4039 1873-3581 |
DOI: | 10.1016/j.tetlet.2016.02.023 |