Early- vs late-onset subcortical vascular cognitive impairment

Early- vs late-onset subcortical vascular cognitive impairment

OBJECTIVE:To evaluate the differences between early-onset subcortical vascular cognitive impairment (EO-SVCI) and late-onset subcortical vascular cognitive impairment (LO-SVCI) with regard to pathologic burden, structural changes, and cognitive function. METHODS:We prospectively recruited 142 patien...

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Veröffentlicht in:Neurology 2016-02, Vol.86 (6), p.527-534
Hauptverfasser: Jang, Young Kyoung, Kwon, Hunki, Kim, Yeo Jin, Jung, Na Yeon, Lee, Jin San, Lee, Juyoun, Chin, Juhee, Im, Kiho, Jeon, Seun, Lee, Jong Min, Seong, Joon-Kyoung, Kim, Jeong Hun, Kim, Seonwoo, Choe, Yearn Seong, Lee, Kyung-Han, Kim, Sung Tae, Kim, Jae Seung, Lee, Jae Hong, Na, Duk L, Seo, Sang Won, Kim, Hee Jin
Format: Artikel
Sprache:eng
Schlagworte:
Adult
Age of Onset
Aged
Aged, 80 and over
Amyloid - metabolism
Brain Mapping
Cerebral Cortex - pathology
Cognition Disorders - pathology
Female
Humans
Magnetic Resonance Imaging - methods
Male
Middle Aged
Neuropsychological Tests
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Zusammenfassung:OBJECTIVE:To evaluate the differences between early-onset subcortical vascular cognitive impairment (EO-SVCI) and late-onset subcortical vascular cognitive impairment (LO-SVCI) with regard to pathologic burden, structural changes, and cognitive function. METHODS:We prospectively recruited 142 patients from a single referral center. Patients were divided into EO-SVCI (n = 30, age at onset
ISSN:0028-3878
1526-632X
DOI:10.1212/WNL.0000000000002357