Symposium report of the 19th annual meeting of the Japanese Society for Vaccinology 2015: What is the role of clinicians in vaccinology?

Preparation for the introduction of a new vaccine requires many efforts such as studies to evaluate the efficacy and safety profiles of the candidate vaccine. [...]it is necessary to determine whether the candidate vaccine should be introduced in our county based on clinical epidemiological studies...

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Veröffentlicht in:Vaccine 2016-07, Vol.34 (34), p.4079-4082
Hauptverfasser: Yoshikawa, Tetsushi, Ihara, Toshiaki, Watanabe, Masahiro, Nishimura, Naoko, Kino, Yoichiro
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Sprache:eng
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Zusammenfassung:Preparation for the introduction of a new vaccine requires many efforts such as studies to evaluate the efficacy and safety profiles of the candidate vaccine. [...]it is necessary to determine whether the candidate vaccine should be introduced in our county based on clinical epidemiological studies and cost benefit analysis. [...]diagnosis of these two common viral infections is major problem in private pediatric clinic. [...]two clinical studies were conducted to establish reliable laboratory methods for the diagnosis of mumps and varicella in private clinics. The numbers of unvaccinated and vaccinated (received at least one vaccine) children that expressed mumps-specific IgM antibodies were 252/289 (87.2%) and 7/67 (10.4%), respectively. [...]the presence of mumps-specific IgM antibodies may be unreliable for diagnosis of children with history of mumps vaccine.
ISSN:0264-410X
1873-2518
DOI:10.1016/j.vaccine.2016.06.030