The Serotonin Reuptake Inhibitor Citalopram Suppresses Activity in the Neonatal Rat Barrel Cortex in vivo

Highlights • Serotonin reuptake inhibitor citalopram inhibits cortical activity in neonatal rats. • Citalopram reduces sensory evoked potentials and oscillations. • Citalopram also inhibits spontaneous activity

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Veröffentlicht in:	Brain research bulletin 2016-06, Vol.124, p.48-54
Hauptverfasser:	Akhmetshina, Dinara, Zakharov, Andrei, Vinokurova, Daria, Nasretdinov, Azat, Valeeva, Guzel, Khazipov, Roustem
Format:	Artikel
Sprache:	eng
Schlagworte:	Age Factors Alkaloids Animals Animals, Newborn Cerebral Cortex - drug effects Citalopram Citalopram - pharmacology Electroencephalogram Evoked Potentials, Somatosensory - drug effects Female In Vitro Techniques Male Neonate Neural Inhibition - drug effects Neurology Rats Rats, Wistar Selective serotonin reuptake inhibitors Serotonin Serotonin Uptake Inhibitors - pharmacology Somatosensory cortex Spectrum Analysis Time Factors
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Beschreibung
Zusammenfassung:	Highlights • Serotonin reuptake inhibitor citalopram inhibits cortical activity in neonatal rats. • Citalopram reduces sensory evoked potentials and oscillations. • Citalopram also inhibits spontaneous activity
ISSN:	0361-9230 1873-2747
DOI:	10.1016/j.brainresbull.2016.03.011