Clinical Characteristics and Prognosis of 123 Patients with Diffuse Large B-cell Lymphoma of Waldeyer's Ring

Objective To investigate the clinical characteristics, prognostic factor and treatment strategy of primary Waldeyer's ring diffuse large B-cell lymphoma(WR-DLBCL) patients. Methods A total of 123 WR-DLBCL patients who were initially diagnosed and treated in Tianjin Medical University Cancer Institute and Hospital from January 2006 to June 2014 were retrospectively analysed, including clinical characteristics, treatment and survival. Kaplan-Meier method was used for evaluating the 3- and 5-year overall survival(OS) rates. Log-rank method was used to evaluate the significance tests. Multivariate analysis was carried out with the Cox proportional hazard model. Results Among 123 patients, the median age was 56(16-80) years old, including 72 males. Twenty patients were Ann Arbor stage, 63 patients were stage, 23 patients were stage III, and 17 patients were stage. After a median follow-up of 54 months, the 3- and 5-year OS were 74.7% and 56.3%, and those of stage-were 84.2% and 69.4%. The univariate analysis revea