Association Between Type-2 Diabetes Mellitus and Platelet Count in Patients with Primary Liver Cancers

Objective To determine the association between type-2 diabetes mellitus (DM) and platelet count in patients with primary liver cancers (PLC). Methods We included 375 patients with a hospital discharge diagnosis of PLC treated in the China-Japan Friendship Hospital from January 2003 to April 2012 in this investigation, according to the diagnostic criteria, inclusion and exclusion criteria. The demographic, clinical, biochemical and metabolic data were analyzed; and the multivariate logistic regression model was used to determine the association between DM and platelet count in PLC patients. Results Of the total 375 patients, 63 (16.8%) cases were diagnosed with DM, the mean neutrophil count was (4.13+ or -2.49)x10 super(9)/L, the mean hemoglobin was (132.5+ or -23.8)g/L, the median/interquartile range of platelet count was 130/(85-189)x10 super(9)/L and the mean international normalized ratio (INR) level was (1.20+ or -0.27). A statistical difference was found by univariate analysis for the platelet count [113