Evaluation of the Abbot ARCHITECT™ Epstein-Barr Virus Viral Capsid Antigen IgM, Viral Capsid Antigen IgG and Nuclear Antigen IgG Assays in a Pediatric and Adult Population

Highlights • VCA IgM, VCA IgG and EBNA IgG CMIAs demonstrate good to excellent agreement with ELISA and IF assays. • VCA IgG and EBNA IgG CMIAs positivity and IF semi-quantitative fluorescence intensity correlate. • Architect™ CMIAs for EBV VCA IgG and EBNA IgG are highly sensitive and specific....

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Veröffentlicht in:	Journal of clinical virology 2016-08, Vol.81, p.1-5
Hauptverfasser:	Grandjean Lapierre, Simon, Vallières, Emilie, Rabaamad, Leila, Labrecque, Manon, Chartrand, Caroline, Renaud, Christian
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Adult Aged Aged, 80 and over Allergy and Immunology Antibodies, Viral - blood Capsid Proteins - immunology Chemiluminescent microparticle immunoassay Child Child, Preschool Enzyme linked immunosorbent assay Epstein-Barr virus Epstein-Barr Virus Infections - diagnosis Epstein-Barr Virus Infections - immunology Epstein-Barr Virus Infections - virology Epstein-Barr Virus Nuclear Antigens - immunology Female Herpesvirus 4, Human - immunology Humans Immunoassay - methods Immunoassay - standards Immunofluorescence Immunoglobulin G - blood Immunoglobulin M - blood Infant Infant, Newborn Infectious Disease Infectious mononucleosis Luminescent Measurements Male Middle Aged Reproducibility of Results Sensitivity and Specificity Young Adult
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Beschreibung
Zusammenfassung:	Highlights • VCA IgM, VCA IgG and EBNA IgG CMIAs demonstrate good to excellent agreement with ELISA and IF assays. • VCA IgG and EBNA IgG CMIAs positivity and IF semi-quantitative fluorescence intensity correlate. • Architect™ CMIAs for EBV VCA IgG and EBNA IgG are highly sensitive and specific.
ISSN:	1386-6532 1873-5967
DOI:	10.1016/j.jcv.2016.05.008