O-017Right Ventricular Function In Infants With Severe Bronchiolitis And Different Respiratory Support

Background and aimsCardiac dysfunction during bronchiolitis has been reported but few studies have assessed right ventricular function (RVF). The aim of this study was to assess RVF in infants with severe bronchiolitis with different respiratory support.MethodsProspective study of under 3-month-old infants admitted to the PICU for severe bronchiolitis. Patients were classified in 3 groups according to the respiratory support: CPAP, bilevel positive airway pressure (BLPAP) and mechanical ventilation (MV). If the respiratory support was changed, echocardiography was repeated. Morphology and systolic and diastolic function were evaluated by echocardiography including Tissue Doppler imaging (TDI).Results30 echocardiographies were performed: 9 in infants with CPAP (4-8 cmH2O), 10 in BLPAP (13-16 cmH2O/6-8 cmH2O) and 10 in MV (PEEP 5-9 cmH2O and MAP 9-17 cmH2O). There was no difference in age or weight between the groups. The most relevant results are shown in Table 1.ConclusionsAs respiratory support increases, decreased systolic and diastolic RVF is observed by TDI in infants with severe bronchiolitis.Abstract O-017 Table 1Description of right ventricular function in infants with bronchiolitis with different respiratory support Characteristics CPAP(9)# BLPAP(10)# MV(11)# p Age (Days)52 (26-90)49 (16-78)45 (16-72)0,714Weight (Kg)4,0 (3-5,5)4,2 (3,3-6)4,2 (3,5-5,5)0,611Right sphericity index1,8 (1,49-2,34)2,1 (1,7-2,85)2,1 (1,52-2,64)0,102Base-to-apex length (mm)25,6 (23,7-27,227,8 (22,9-31,3)28,4 (26,3-34)0,002Tricuspid annulus s' (cm/s)10 (6,7-14)9,2 (6,7-14,6)7,4 (4,2-10)0,035Tricuspid annulus e' (cm/s)11,6 (9,6-15)10,5 (7,5-16,9)8,0 (4,5-10,1)0,001Tricuspid E/A ratio1,2 (0,9-2,0)1,1 (0,6-1,8)1,0 (0,7-1,8)0,140 # Mean (Range).