Mood and metabolism: Anhedonia as a clinical target in Type 2 diabetes

Highlights • In Type 2 diabetes anhedonic symptoms are associated with poor glycemic control and mortality, mediated by behavioural factors. • Anhedonic symptoms may arise from neuroendocrine effects on dopaminergic reward pathways. • Screening and treatment of anhedonia may improve psychological an...

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Veröffentlicht in:	Psychoneuroendocrinology 2016-07, Vol.69, p.123-132
Hauptverfasser:	Carter, Jasmine, Swardfager, Walter
Format:	Artikel
Sprache:	eng
Schlagworte:	Affect - physiology Anhedonia Anhedonia - physiology Brain - metabolism Depression Depression - physiopathology Depressive Disorder - physiopathology Diabetes Diabetes Mellitus, Type 2 - complications Diabetes Mellitus, Type 2 - metabolism Diabetes Mellitus, Type 2 - psychology Dopamine Dopamine - metabolism Dopamine Agents - metabolism Drive Endocrinology & Metabolism Humans Insulin Motivation Motivation - physiology Psychiatry Reward
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Beschreibung
Zusammenfassung:	Highlights • In Type 2 diabetes anhedonic symptoms are associated with poor glycemic control and mortality, mediated by behavioural factors. • Anhedonic symptoms may arise from neuroendocrine effects on dopaminergic reward pathways. • Screening and treatment of anhedonia may improve psychological and clinical outcomes in Type 2 diabetes.
ISSN:	0306-4530 1873-3360
DOI:	10.1016/j.psyneuen.2016.04.002