Association of pain intensity, pain-related disability, and depression with hypothalamus-pituitary-adrenal axis function in female patients with chronic temporomandibular disorders

Highlights • The HPA axis function in the female patients with chronic TMD was examined. • Cortisol secretion was comparable between patients and healthy controls. • Cortisol/DHEA ratio was increased with pain intensity and pain-related disability. • Cortisol/DHEA ratio was increased with severity o...

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Veröffentlicht in:Psychoneuroendocrinology 2016-07, Vol.69, p.106-115
Hauptverfasser: Jo, Kyung B, Lee, Young J, Lee, Il G, Lee, Sang C, Park, Jai Y, Ahn, Ryun S
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Sprache:eng
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Zusammenfassung:Highlights • The HPA axis function in the female patients with chronic TMD was examined. • Cortisol secretion was comparable between patients and healthy controls. • Cortisol/DHEA ratio was increased with pain intensity and pain-related disability. • Cortisol/DHEA ratio was increased with severity of depression. • The results show dissociation between cortisol and DHEA secretions in TMD patients.
ISSN:0306-4530
1873-3360
DOI:10.1016/j.psyneuen.2016.03.017