Chronic pacing and adverse outcomes after transcatheter aortic valve implantation

ObjectiveMany patients undergoing transcatheter aortic valve implantation (TAVI) have a pre-existing, permanent pacemaker (PPM) or receive one as a consequence of the procedure. We hypothesised that chronic pacing may have adverse effects on TAVI outcomes.Methods and resultsFour groups of patients u...

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Veröffentlicht in:	Heart (British Cardiac Society) 2015-10, Vol.101 (20), p.1665-1671
Hauptverfasser:	Dizon, Jose’ M, Nazif, Tamim M, Hess, Paul L, Biviano, Angelo, Garan, Hasan, Douglas, Pamela S, Kapadia, Samir, Babaliaros, Vasilis, Herrmann, Howard C, Szeto, Wilson Y, Jilaihawi, Hasan, Fearon, William F, Tuzcu, E Murat, Pichard, Augusto D, Makkar, Raj, Williams, Mathew, Hahn, Rebecca T, Xu, Ke, Smith, Craig R, Leon, Martin B, Kodali, Susheel K
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged, 80 and over Aortic Valve Stenosis - complications Aortic Valve Stenosis - mortality Aortic Valve Stenosis - surgery Bundle-Branch Block - complications Bundle-Branch Block - mortality Bundle-Branch Block - therapy Cardiovascular disease Chronic obstructive pulmonary disease Clinical outcomes Coronary vessels Electrocardiography Female Follow-Up Studies Humans Male Morphology Mortality Pacemaker, Artificial - adverse effects Prognosis Survival Rate - trends Transcatheter Aortic Valve Replacement Treatment Outcome United States - epidemiology Variables
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Zusammenfassung:	ObjectiveMany patients undergoing transcatheter aortic valve implantation (TAVI) have a pre-existing, permanent pacemaker (PPM) or receive one as a consequence of the procedure. We hypothesised that chronic pacing may have adverse effects on TAVI outcomes.Methods and resultsFour groups of patients undergoing TAVI in the Placement of Aortic Transcatheter Valves (PARTNER) trial and registries were compared: prior PPM (n=586), new PPM (n=173), no PPM (n=1612), and left bundle branch block (LBBB)/no PPM (n=160). At 1 year, prior PPM, new PPM and LBBB/no PPM had higher all-cause mortality than no PPM (27.4%, 26.3%, 27.7% and 20.0%, p
ISSN:	1355-6037 1468-201X
DOI:	10.1136/heartjnl-2015-307666