Tissue Engineering: Mechanocompatible Polymer-Extracellular-Matrix Composites for Vascular Tissue Engineering (Adv. Healthcare Mater. 13/2016)

Tissue Engineering: Mechanocompatible Polymer-Extracellular-Matrix Composites for Vascular Tissue Engineering (Adv. Healthcare Mater. 13/2016)

Heparinized mechanocompatible polymer‐extracellular matrix (ECM) composites to improve vascular graft performance are presented by J. A. Wertheim, G. A. Ameer, and co‐workers on page 1594. Polymer‐coated ECM is visualized by the purple color. The composite vascular graft reduced intimal hyperplasia...

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Veröffentlicht in:Advanced healthcare materials 2016-07, Vol.5 (13), p.1593-1593
Hauptverfasser: Jiang, Bin, Suen, Rachel, Wang, Jiao-Jing, Zhang, Zheng J., Wertheim, Jason A., Ameer, Guillermo A.
Format: Artikel
Sprache:eng
Schlagworte:
8-octamethylene citrate) (POC
composite
extracellular matrix (ECM)
heparin
poly
poly(1,8‐octamethylene citrate) (POC)
Tissue engineering
vascular graft
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Zusammenfassung:Heparinized mechanocompatible polymer‐extracellular matrix (ECM) composites to improve vascular graft performance are presented by J. A. Wertheim, G. A. Ameer, and co‐workers on page 1594. Polymer‐coated ECM is visualized by the purple color. The composite vascular graft reduced intimal hyperplasia in a rodent model, revealed by α‐smooth muscle actin staining (green). The method shows promise for tissue engineering where immobilization of bioactive molecules is desirable.
ISSN:2192-2640
2192-2659
DOI:10.1002/adhm.201670067