PO-0494Longterm Multichannel Nirs Monitorization Is Feasable And Valuable In Multisystem Disease Of Term Newborns

BackgroundNear infrared spectroscopy (NIRS) is evolving into a clinical monitorization method providing information regarding not only cerebral but abdominal or renal tissue oxygenation (rSO2) as well. Fractional tissue oxygen extraction (FTOE) is calculated from NIRS measurements and arterial haemoglobin oxygen saturation (SpO2) measured by pulse oxymeter. Multichannel NIRS devices maybe very helpful in newborns with multisystem problems enabling realtime simultaneous measurements of rSO2 from different parts of the body. Pulse oxymeter integrated into a multichannel NIRS device provides simultaneous SpO2 monitoring making FTOE calculations more accurate and easier.MethodsThree term newborns; 2 undergoing therapeutic hypothermia for hypoxic ischaemic encephalopathy grade II, 1 with critical pulmonary stenosis before and after cardiac surgery were monitored by multichannel NIRS (Sensmart X-100, NONIN, USA) device including cerebral, abdominal, renal rSO2 and SpO2 probes. FTOE was calculated using the equation; (SpO2-rSO2)/SpO2.ResultsDuration of monitorization and rSO2 and FTOE values of different body sites are presented in table with mean plus or minus SD.Abstract PO-0494 Table 1 Patient No Duration (h) Cerebral-rSO2 c-FTOE Abdominal-rSO2 a-FTOE Renal-rSO2 r-FTOE 1 (58)73 plus or minus 6,90,2 plus or minus 0,0777 plus or minus 6,40,2 plus or minus 0,0371 plus or minus 6,80,2 plus or minus 0,052 (68)78 plus or minus 30,2 plus or minus 0,0177 plus or minus 5,50,2 plus or minus 0,0378 plus or minus 5,20,2 plus or minus 0,013 before surgery on PGE1 (112)57 plus or minus 6,80,3 plus or minus 0,0763 plus or minus 8,50,2 plus or minus 0,0872 plus or minus 7,20,1 plus or minus 0,084 after surgery (25)64 plus or minus 3,60,1 plus or minus 0,0568 plus or minus 0,60,02 plus or minus 0,00161 plus or minus 3,20,1 plus or minus 0,05DiscussionLongterm simultaneous monitoring of tissue oxygenation in brain, abdomen and kidneys is useful while following newborns with multisystem problems requiring hypothermia or circulatory medications to titrate the treatment accordingly. NIRS device with integrated pulse oxymeter maybe helpful for realtime calculation of FTOE to assess hemodynamics.