PO-0495Intravenous Ibuprofen (ibu) Vs Continuous Indomethacin-infusion (ind-inf) For Symptomatic Patent Ductus Arteriosus (pda) Treatment In Newborns

PO-0495Intravenous Ibuprofen (ibu) Vs Continuous Indomethacin-infusion (ind-inf) For Symptomatic Patent Ductus Arteriosus (pda) Treatment In Newborns

BackgroundIBU is equivalent to IND for PDA-treatment. IBU reduces less cerebral, mesenteric and renal perfusion and platelet function. IND-INF seems to have similar effects on circulation, but the clinical efficacy of this approach is unclear.AimTo compare the efficacy and safety of PDA-treatment us...

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Veröffentlicht in:Archives of disease in childhood 2014-10, Vol.99 (Suppl 2), p.A410-A410
Hauptverfasser: Storring, N, Amess, P, Aiton, N, Bomont, R, Rabe, H, Alvarez, Fernandez
Format: Artikel
Sprache:eng
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Zusammenfassung:BackgroundIBU is equivalent to IND for PDA-treatment. IBU reduces less cerebral, mesenteric and renal perfusion and platelet function. IND-INF seems to have similar effects on circulation, but the clinical efficacy of this approach is unclear.AimTo compare the efficacy and safety of PDA-treatment using 36-hour IND-INF vs IBU in preterm infants.MethodsRetrospective matched-pair cohort-analysis of infants
ISSN:0003-9888
DOI:10.1136/archdischild-2014-307384.1141