The randomised complete vs. lesion only primary PCI trial - cardiovascular MRI substudy (CVLPRIT-CMR)

Background: Multivessel disease (MVD) occurs in ~40% of STEMI. Management is controversial. PRAMI and CVLPRIT showed improved clinical outcomes with complete versus infarct-related artery (IRA)-only revascularisation at primary percutaneous coronary intervention (PPCI). However, non-IRA PCI may caus...

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Veröffentlicht in:Heart (British Cardiac Society) 2015-04, Vol.101 (Suppl 2), p.A10-A11
Hauptverfasser: Khan, J N, Greenwood, J P, Nazir, SA, Dalby, M, Curzen, N, Hetherington, S, Kelly, D J, Blackman, D, Ring, A, Peebles, C, Wong, J, Flather, M, Swanton, H, Gershlick, AH, McCann, G P
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Sprache:eng
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Zusammenfassung:Background: Multivessel disease (MVD) occurs in ~40% of STEMI. Management is controversial. PRAMI and CVLPRIT showed improved clinical outcomes with complete versus infarct-related artery (IRA)-only revascularisation at primary percutaneous coronary intervention (PPCI). However, non-IRA PCI may cause additional infarcts. We aimed to determine whether in-hospital complete revascularisation was associated with increased myocardial injury versus an IRA-only strategy. Methods: Multicentre, prospective, randomised, blinded endpoint trial. STEMI patients with MVD and
ISSN:1355-6037
1468-201X
DOI:10.1136/heartjnl-2015-307845.19