Discipline with refining in my career in pancreatology

Using animal models, we had studied extensively the role of pancreatic PLA2 (type I sPLA2) in the pathophysiology of acute pancreatitis, and the results suggested a strong association with the development of pancreatic necrosis, pulmonary damage through the destruction of alveolar surfactant, and renal tubular damage. Since the discovery of nonpancreatic sPLAs (type II), type II sPLA2 has also been found to be associated with aggravation of pancreatitis. Furthermore, we revealed that remnant pancreatic volume and status of postoperative infection paradoxically influenced the development of NAFLD after PD. Organ-preserving pancreatectomies have been used for the treatment of benign and sometime, malignant diseases of the pancreatic head region.