Reduction of Sulfoxides with Ascorbic Acid Catalyzed by NBS

An efficient procedure to reduce sulfoxides using ascorbic acid has been developed. Using this procedure structurally diverse sulfoxides were reduced by treating with ascorbic acid in the presence of a catalytic amount of N-bromosuccinimide (NBS) at room temperature in high yields.

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Veröffentlicht in:Bulletin of the Chemical Society of Japan 2016-03, Vol.89 (3), p.405-407
Hauptverfasser: Abbasi, Mohammad, Mohammadizadeh, Mohammad Reza, Moradi, Zahra
Format: Artikel
Sprache:eng
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Zusammenfassung:An efficient procedure to reduce sulfoxides using ascorbic acid has been developed. Using this procedure structurally diverse sulfoxides were reduced by treating with ascorbic acid in the presence of a catalytic amount of N-bromosuccinimide (NBS) at room temperature in high yields.
ISSN:0009-2673
1348-0634
DOI:10.1246/bcsj.20150296