Frontispiece: Chemoenzymatic Synthesis of Pleiogenone A: An Antiproliferative Trihydroxyalkylcyclohexenone Isolated from Pleiogynium timorense

Natural Products Pleiogenone A, which has been isolated from Pleiogynium timorense, has been synthesized for the first time. The synthesis confirms the previously reported structure as well as the absolute configuration. The route started with the enzymatic dihydroxylation of inexpensive and readily...

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Veröffentlicht in:	Chemistry : a European journal 2016-04, Vol.22 (18), p.np-n/a
Hauptverfasser:	Froese, Jordan, Overbeeke, Cameron, Hudlicky, Tomas
Format:	Artikel
Sprache:	eng
Schlagworte:	anticancer activity Antiproliferatives Benzoic acid Chemistry enzymatic dihydroxylation Natural products Pleiogynium timorense singlet oxygen cycloaddition Synthesis trihydroxyalkylcyclohexenones
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