Remote Measurement of Respiratory Rate in Laboratory Mice during Studies of mdx-Model of Progressive Duchenne Muscular Dystrophy

Remote Measurement of Respiratory Rate in Laboratory Mice during Studies of mdx-Model of Progressive Duchenne Muscular Dystrophy

Hardware and software for measuring respiration rate in mice are described. The design is based on slightly modified source code of the QPULSECAPTURE project. The measuring device based on an 86x PC and a webcam enables measurements with absolute error of 18 breaths/min in the frequency range from 2...

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Veröffentlicht in:Biomedical engineering 2015-07, Vol.49 (2), p.79-84
Hauptverfasser: Stenina, M. A., Krivov, L. I., Spiridonov, I. N., Taranov, A. A.
Format: Artikel
Sprache:eng
Schlagworte:
Biomaterials
Biomedical engineering
Biomedical Engineering and Bioengineering
Comparative studies
Computer programs
Devices
Duchenne muscular dystrophy
Duchenne's muscular dystrophy
Dystrophin
Engineering
Error analysis
Frequency ranges
Genetic aspects
Laboratory animals
Measurement
Measuring instruments
Mice
Monitoring systems
Muscular dystrophy
Respiration
Respiratory rate
Respiratory system
Software
Source code
Utrophin
Webcams
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Beschreibung
Zusammenfassung:Hardware and software for measuring respiration rate in mice are described. The design is based on slightly modified source code of the QPULSECAPTURE project. The measuring device based on an 86x PC and a webcam enables measurements with absolute error of 18 breaths/min in the frequency range from 200 to 320 breaths/min. The device was used for comparative study of a group of mdx-mice with mutated dystrophin gene and a normal control group. It was found that the respiration rate in the mdx-mouse group was significantly higher.
ISSN:0006-3398
1573-8256
DOI:10.1007/s10527-015-9502-1