Synthesis and Study of Norfloxacin Labeled with Technecium-99m as a Potential Imaging Agent of Bacterial Inflammations

Investigations have been carried out into creation of reagent for labeled norfloxacin hydrochloride (NFH).Methods: The NFH synthesized in the Institute of Organic Synthesis (Ekaterinburg) was used in this research. The effect of the mixture components on the radiochemical specimen purity was assesse...

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Veröffentlicht in:Key Engineering Materials 2016-02, Vol.685, p.798-802
Hauptverfasser: Sazonov, Aleksey E., Nesterov, Evgeniy A., Skuridin, Viktor S., Larionova, Liudmila A., Varlamova, Natalya V., Sazonova, Svetlana I.
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Sprache:eng
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Zusammenfassung:Investigations have been carried out into creation of reagent for labeled norfloxacin hydrochloride (NFH).Methods: The NFH synthesized in the Institute of Organic Synthesis (Ekaterinburg) was used in this research. The effect of the mixture components on the radiochemical specimen purity was assessed using the method of thin-layer chromatography.Results: The inflammation animal model was used to demonstrate the NFH functional eligibility for diagnostics of inflammatory processes.
ISSN:1013-9826
1662-9795
1662-9795
DOI:10.4028/www.scientific.net/KEM.685.798