A rapid high throughput proteomic method based on profiling of proteolytic free peptides to assess post-delivery degradation of placental tissue

Abstract A rapid method to determine quality for placental proteomic studies is required due to varying lengths of time between delivery and sampling in routine protocols. We developed a rapid 10 min LC-MS based scanning method to profile free peptides liberated from natural proteolytic degradation....

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Veröffentlicht in:	Placenta (Eastbourne) 2016-08, Vol.44, p.109-111
Hauptverfasser:	Heywood, Wendy E, Pryce, Jeremy, Virasami, Alex, Preece, Rhian Lauren, Dezateux, Carol, Mills, Kevin, Sebire, Neil J
Format:	Artikel
Sprache:	eng
Schlagworte:	Chromatography, Liquid Delivery, Obstetric Female Free peptide Humans Internal Medicine LC-MS Mass Spectrometry Multivariate analysis Obstetrics and Gynecology Placenta Placenta - metabolism Placenta - pathology Pregnancy Proteolysis Proteomics - methods Specimen Handling
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