Effects of atorvastatin on conservative and surgical treatments of chronic subdural hematoma in patients

Abstract Objective To investigate effects of atorvastatin on conservative and surgical treatments of chronic subdural hematoma in patients. Methods A retrospective analysis was performed in 109 (including 3 outpatients) CSDH patients of Northern Jiangsu People's Hospital from April，2014 to Oct 2015. Patients’ gender, age, Glasgow Coma Scale (GCS), symptoms, history of antiplatelet or anticoagulant, hematoma location, volume of hematoma, operation methods, application of atorvastatin and its duration were recorded. Prognostic indicators including changes in hematoma volume and neurological status were extracted. Statistical methods were conducted to evaluate drug efficacy. Results Seven conservative patients received atorvastatin for 1-6 months (3.57 ± 1.72 months). The volume of hematomas were significantly reduced from 20.83 ± 4.49 ml to 11.40 ± 4.46 ml (p