Autocrine/paracrine roles of extrapituitary growth hormone and prolactin in health and disease: An overview

Autocrine/paracrine roles of extrapituitary growth hormone and prolactin in health and disease: An overview

Highlights • GH and prolactin have autocrine or paracrine roles in extrapituitary sites of synthesis. • These roles have functional significance in health or disease. • GH and prolactin are not just pituitary endocrines but local growth factors.

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Bibliographische Detailangaben
Veröffentlicht in:General and comparative endocrinology 2015-09, Vol.220, p.103-111
Hauptverfasser: Harvey, Steve, Martínez-Moreno, Carlos G, Luna, Maricela, Arámburo, Carlos
Format: Artikel
Sprache:eng
Schlagworte:
Autocrine
Autocrine Communication
Endocrinology & Metabolism
Gene Expression
Growth hormone
Human Growth Hormone - genetics
Human Growth Hormone - metabolism
Humans
Paracrine
Paracrine Communication
Pituitary
Pituitary Gland - metabolism
Prolactin
Prolactin - genetics
Prolactin - metabolism
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Beschreibung
Zusammenfassung:Highlights • GH and prolactin have autocrine or paracrine roles in extrapituitary sites of synthesis. • These roles have functional significance in health or disease. • GH and prolactin are not just pituitary endocrines but local growth factors.
ISSN:0016-6480
1095-6840
DOI:10.1016/j.ygcen.2014.11.004