Discovery and functional characterization of leptin and its receptors in Japanese quail ( Coturnix japonica )
Highlights • LEP and four leptin receptor isoforms were obtained firstly in Japanese quail. • qLEP and the four qLEPR isoforms were expressed extensively in all tissues examined. • Fasting increases and refeeding decreases LEP and LEPR expressions of juvenile quail. • LEP may actually act to inhibit...
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Veröffentlicht in: | General and comparative endocrinology 2016-01, Vol.225, p.1-12 |
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container_title | General and comparative endocrinology |
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creator | Wang, Dandan Xu, Chunlin Wang, Taian Li, Hong Li, Yanmin Ren, Junxiao Tian, Yadong Li, Zhuanjian Jiao, Yuping Kang, Xiangtao Liu, Xiaojun |
description | Highlights • LEP and four leptin receptor isoforms were obtained firstly in Japanese quail. • qLEP and the four qLEPR isoforms were expressed extensively in all tissues examined. • Fasting increases and refeeding decreases LEP and LEPR expressions of juvenile quail. • LEP may actually act to inhibit food intake during fasting, at least in juvenile quail. • qLEP and qLEPR may play important roles in regulating reproduction and energy status. |
doi_str_mv | 10.1016/j.ygcen.2015.09.003 |
format | Article |
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Xu, Chunlin ; Wang, Taian ; Li, Hong ; Li, Yanmin ; Ren, Junxiao ; Tian, Yadong ; Li, Zhuanjian ; Jiao, Yuping ; Kang, Xiangtao ; Liu, Xiaojun</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c517t-2c3b9aea88a2acd6ff638f5808218218eea563f16bd4a8af4be7126e765a6e23</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2016</creationdate><topic>Age Factors</topic><topic>Alternative splicing</topic><topic>Amino Acid Sequence</topic><topic>Animals</topic><topic>Carrier Proteins - metabolism</topic><topic>Cloning, Molecular</topic><topic>Coturnix - metabolism</topic><topic>Eating - genetics</topic><topic>Endocrinology & Metabolism</topic><topic>Exons</topic><topic>Female</topic><topic>Gene cloning</topic><topic>Hypothalamus - metabolism</topic><topic>LEPR</topic><topic>Leptin</topic><topic>Leptin - genetics</topic><topic>Leptin - metabolism</topic><topic>Ovary - metabolism</topic><topic>Physiological function</topic><topic>Pituitary Gland - metabolism</topic><topic>Quail</topic><topic>Receptors, Leptin - genetics</topic><topic>Receptors, Leptin - metabolism</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Wang, Dandan</creatorcontrib><creatorcontrib>Xu, Chunlin</creatorcontrib><creatorcontrib>Wang, Taian</creatorcontrib><creatorcontrib>Li, Hong</creatorcontrib><creatorcontrib>Li, Yanmin</creatorcontrib><creatorcontrib>Ren, Junxiao</creatorcontrib><creatorcontrib>Tian, Yadong</creatorcontrib><creatorcontrib>Li, Zhuanjian</creatorcontrib><creatorcontrib>Jiao, Yuping</creatorcontrib><creatorcontrib>Kang, Xiangtao</creatorcontrib><creatorcontrib>Liu, Xiaojun</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><collection>Environmental Sciences and Pollution Management</collection><collection>ASFA: Aquatic Sciences and Fisheries Abstracts</collection><collection>Aquatic Science & Fisheries Abstracts (ASFA) 3: Aquatic Pollution & Environmental Quality</collection><collection>Aquatic Science & Fisheries Abstracts (ASFA) Professional</collection><jtitle>General and comparative endocrinology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Wang, Dandan</au><au>Xu, Chunlin</au><au>Wang, Taian</au><au>Li, Hong</au><au>Li, Yanmin</au><au>Ren, Junxiao</au><au>Tian, Yadong</au><au>Li, Zhuanjian</au><au>Jiao, Yuping</au><au>Kang, Xiangtao</au><au>Liu, Xiaojun</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Discovery and functional characterization of leptin and its receptors in Japanese quail ( Coturnix japonica )</atitle><jtitle>General and comparative endocrinology</jtitle><addtitle>Gen Comp Endocrinol</addtitle><date>2016-01-01</date><risdate>2016</risdate><volume>225</volume><spage>1</spage><epage>12</epage><pages>1-12</pages><issn>0016-6480</issn><eissn>1095-6840</eissn><abstract>Highlights • LEP and four leptin receptor isoforms were obtained firstly in Japanese quail. • qLEP and the four qLEPR isoforms were expressed extensively in all tissues examined. • Fasting increases and refeeding decreases LEP and LEPR expressions of juvenile quail. • LEP may actually act to inhibit food intake during fasting, at least in juvenile quail. • qLEP and qLEPR may play important roles in regulating reproduction and energy status.</abstract><cop>United States</cop><pub>Elsevier Inc</pub><pmid>26342967</pmid><doi>10.1016/j.ygcen.2015.09.003</doi><tpages>12</tpages></addata></record> |
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subjects | Age Factors Alternative splicing Amino Acid Sequence Animals Carrier Proteins - metabolism Cloning, Molecular Coturnix - metabolism Eating - genetics Endocrinology & Metabolism Exons Female Gene cloning Hypothalamus - metabolism LEPR Leptin Leptin - genetics Leptin - metabolism Ovary - metabolism Physiological function Pituitary Gland - metabolism Quail Receptors, Leptin - genetics Receptors, Leptin - metabolism |
title | Discovery and functional characterization of leptin and its receptors in Japanese quail ( Coturnix japonica ) |
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