Thyroplasty in the previously irradiated neck: A case series and short-term outcomes

Objectives/Hypothesis External beam radiation to the neck is widely considered a contraindication for thyroplasty due to concern for infection and implant extrusion. We present a case series of our experience regarding thyroplasty performed in a previously radiated field. Study Design Retrospective...

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Veröffentlicht in:The Laryngoscope 2016-08, Vol.126 (8), p.1849-1853
Hauptverfasser: White, James R., Orbelo, Diana M., Noel, Daniel B., Pittelko, Rebecca L., Maragos, Nicolas E., Ekbom, Dale C.
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container_end_page 1853
container_issue 8
container_start_page 1849
container_title The Laryngoscope
container_volume 126
creator White, James R.
Orbelo, Diana M.
Noel, Daniel B.
Pittelko, Rebecca L.
Maragos, Nicolas E.
Ekbom, Dale C.
description Objectives/Hypothesis External beam radiation to the neck is widely considered a contraindication for thyroplasty due to concern for infection and implant extrusion. We present a case series of our experience regarding thyroplasty performed in a previously radiated field. Study Design Retrospective case study at a tertiary academic referral center. Methods Using the institution's clinical notes search tool, records from 1999 through 2014 documenting thyroplasty and radiation were identified and reviewed. Patients who received external beam radiation to the operative field prior to thyroplasty were included. Data including duration of radiation, timing and specifics of thyroplasty, postoperative complications, risk factors, clinical voice outcomes, and length of follow‐up were collected. Results Fourteen patients met criteria for the study. Of all thyroplasty performed, 11 were Silastic implants, two were Gore‐Tex implants, six had concurrent arytenoid adduction, and one was a midline type II thyroplasty. In terms of risk factors for postoperative complications, two were diabetic, none were active smokers, and one had a splenectomy. All patients were given postoperative antibiotics. The median duration of follow‐up after surgery was 14.2 months. No patients were found to have postoperative complications. Pre‐ and postoperative voice data were assessed. Overall, there was improvement in voice outcomes. Conclusions Thyroplasty may be an option for patients who have previously undergone external beam radiation. Short‐term and intermediate outcomes in our patients showed no postoperative complications, and generally voice or dysphagia improved. Careful selection is still warranted when considering thyroplasty in a previously irradiated neck, and long‐term outcomes need further study. Level of Evidence 4 Laryngoscope, 126:1849–1853, 2016
doi_str_mv 10.1002/lary.25770
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We present a case series of our experience regarding thyroplasty performed in a previously radiated field. Study Design Retrospective case study at a tertiary academic referral center. Methods Using the institution's clinical notes search tool, records from 1999 through 2014 documenting thyroplasty and radiation were identified and reviewed. Patients who received external beam radiation to the operative field prior to thyroplasty were included. Data including duration of radiation, timing and specifics of thyroplasty, postoperative complications, risk factors, clinical voice outcomes, and length of follow‐up were collected. Results Fourteen patients met criteria for the study. Of all thyroplasty performed, 11 were Silastic implants, two were Gore‐Tex implants, six had concurrent arytenoid adduction, and one was a midline type II thyroplasty. In terms of risk factors for postoperative complications, two were diabetic, none were active smokers, and one had a splenectomy. All patients were given postoperative antibiotics. The median duration of follow‐up after surgery was 14.2 months. No patients were found to have postoperative complications. Pre‐ and postoperative voice data were assessed. Overall, there was improvement in voice outcomes. Conclusions Thyroplasty may be an option for patients who have previously undergone external beam radiation. Short‐term and intermediate outcomes in our patients showed no postoperative complications, and generally voice or dysphagia improved. Careful selection is still warranted when considering thyroplasty in a previously irradiated neck, and long‐term outcomes need further study. 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We present a case series of our experience regarding thyroplasty performed in a previously radiated field. Study Design Retrospective case study at a tertiary academic referral center. Methods Using the institution's clinical notes search tool, records from 1999 through 2014 documenting thyroplasty and radiation were identified and reviewed. Patients who received external beam radiation to the operative field prior to thyroplasty were included. Data including duration of radiation, timing and specifics of thyroplasty, postoperative complications, risk factors, clinical voice outcomes, and length of follow‐up were collected. Results Fourteen patients met criteria for the study. Of all thyroplasty performed, 11 were Silastic implants, two were Gore‐Tex implants, six had concurrent arytenoid adduction, and one was a midline type II thyroplasty. In terms of risk factors for postoperative complications, two were diabetic, none were active smokers, and one had a splenectomy. All patients were given postoperative antibiotics. The median duration of follow‐up after surgery was 14.2 months. No patients were found to have postoperative complications. Pre‐ and postoperative voice data were assessed. Overall, there was improvement in voice outcomes. Conclusions Thyroplasty may be an option for patients who have previously undergone external beam radiation. Short‐term and intermediate outcomes in our patients showed no postoperative complications, and generally voice or dysphagia improved. Careful selection is still warranted when considering thyroplasty in a previously irradiated neck, and long‐term outcomes need further study. Level of Evidence 4 Laryngoscope, 126:1849–1853, 2016</description><subject>Adult</subject><subject>Aged</subject><subject>Female</subject><subject>Humans</subject><subject>irradiated</subject><subject>Laryngeal Neoplasms - surgery</subject><subject>Laryngoplasty - methods</subject><subject>Male</subject><subject>medialization laryngoplasty</subject><subject>Middle Aged</subject><subject>Neck - radiation effects</subject><subject>Postoperative Complications - epidemiology</subject><subject>Prostheses and Implants</subject><subject>radiation</subject><subject>Retrospective Studies</subject><subject>Thyroplasty</subject><subject>Time Factors</subject><subject>Treatment Outcome</subject><issn>0023-852X</issn><issn>1531-4995</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2016</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9kF1LwzAUQIMobk5f_AGSRxE6k6ZpWt_GcFMYE8bEj5eQpTesrl1n0qr792bu49GnwM25h8tB6JKSLiUkvC2UXXdDLgQ5Qm3KGQ2iNOXHqO0_WZDw8LWFzpz7IIQKxskpaoUxD2MmeBtNp_O1rVaFcvUa50tczwGvLHzlVeMKP7FWZbmqIcNL0Is73MNaOcAObA4Oq2WG3byydVCDLXHV1LoqwZ2jE6MKBxe7t4OeB_fT_kMweho-9nujQEdMkGAWggg1ZdSYzIjUEJPM0kQkRilNUwFKGZZFZuavjSDlOjM8TZiIYoh5AjRjHXS99a5s9dmAq2WZOw1FoZbg75c0ITxKIkZSj95sUW0r5ywYubJ56cNJSuSmotxUlH8VPXy18zazErIDus_mAboFvvMC1v-o5Kg3edtLg-1O7mr4Oewou5Cx8FL5Mh7Kcf99PBmMJzJiv10sjag</recordid><startdate>201608</startdate><enddate>201608</enddate><creator>White, James R.</creator><creator>Orbelo, Diana M.</creator><creator>Noel, Daniel B.</creator><creator>Pittelko, Rebecca L.</creator><creator>Maragos, Nicolas E.</creator><creator>Ekbom, Dale C.</creator><general>Blackwell Publishing Ltd</general><scope>BSCLL</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>201608</creationdate><title>Thyroplasty in the previously irradiated neck: A case series and short-term outcomes</title><author>White, James R. ; Orbelo, Diana M. ; Noel, Daniel B. ; Pittelko, Rebecca L. ; Maragos, Nicolas E. ; Ekbom, Dale C.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c4370-b2e72c131ffdf79f0f8b9878faac197eaaf3d4fb2654e95cdf5983746e658e1d3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2016</creationdate><topic>Adult</topic><topic>Aged</topic><topic>Female</topic><topic>Humans</topic><topic>irradiated</topic><topic>Laryngeal Neoplasms - surgery</topic><topic>Laryngoplasty - methods</topic><topic>Male</topic><topic>medialization laryngoplasty</topic><topic>Middle Aged</topic><topic>Neck - radiation effects</topic><topic>Postoperative Complications - epidemiology</topic><topic>Prostheses and Implants</topic><topic>radiation</topic><topic>Retrospective Studies</topic><topic>Thyroplasty</topic><topic>Time Factors</topic><topic>Treatment Outcome</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>White, James R.</creatorcontrib><creatorcontrib>Orbelo, Diana M.</creatorcontrib><creatorcontrib>Noel, Daniel B.</creatorcontrib><creatorcontrib>Pittelko, Rebecca L.</creatorcontrib><creatorcontrib>Maragos, Nicolas E.</creatorcontrib><creatorcontrib>Ekbom, Dale C.</creatorcontrib><collection>Istex</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>The Laryngoscope</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>White, James R.</au><au>Orbelo, Diana M.</au><au>Noel, Daniel B.</au><au>Pittelko, Rebecca L.</au><au>Maragos, Nicolas E.</au><au>Ekbom, Dale C.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Thyroplasty in the previously irradiated neck: A case series and short-term outcomes</atitle><jtitle>The Laryngoscope</jtitle><addtitle>The Laryngoscope</addtitle><date>2016-08</date><risdate>2016</risdate><volume>126</volume><issue>8</issue><spage>1849</spage><epage>1853</epage><pages>1849-1853</pages><issn>0023-852X</issn><eissn>1531-4995</eissn><abstract>Objectives/Hypothesis External beam radiation to the neck is widely considered a contraindication for thyroplasty due to concern for infection and implant extrusion. 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subjects Adult
Aged
Female
Humans
irradiated
Laryngeal Neoplasms - surgery
Laryngoplasty - methods
Male
medialization laryngoplasty
Middle Aged
Neck - radiation effects
Postoperative Complications - epidemiology
Prostheses and Implants
radiation
Retrospective Studies
Thyroplasty
Time Factors
Treatment Outcome
title Thyroplasty in the previously irradiated neck: A case series and short-term outcomes
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