Bilateral lower limb weakness in acute severe ulcerative colitis

An obese 49-year-old man with no medical history of note presented in August, 2014, with a 5-week history of bloody diarrhoea, anorexia, and unintentional weight loss. He reported passing 20 bloody stools per day, with nocturnal disturbance, and on admission had pyrexia, tachycardia, anaemia, and a...

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Veröffentlicht in:	The Lancet (British edition) 2016-07, Vol.388 (10039), p.101-102
Hauptverfasser:	Lynch, Ruairi W, MB, Soane, Timothy, PhD, Gibson, Rod, MB, Pal, Suvankar, MD, Lees, Charlie W, Dr
Format:	Artikel
Sprache:	eng
Schlagworte:	Colitis, Ulcerative - complications Colitis, Ulcerative - diagnosis Colitis, Ulcerative - drug therapy Cyclosporine - therapeutic use Eating disorders Epidural Space Glucocorticoids - therapeutic use Histopathology Humans Immunosuppressive Agents - therapeutic use Inflammatory bowel disease Internal Medicine Legs Lipomatosis - complications Lipomatosis - diagnosis Lower Extremity Lumbar Vertebrae Magnetic Resonance Imaging Male Medical diagnosis Medical treatment Middle Aged Muscle Weakness - diagnosis Muscle Weakness - etiology Obesity - complications Prednisolone - therapeutic use Spinal Cord Compression - complications Spinal Cord Compression - diagnosis Thoracic Vertebrae
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Beschreibung
Zusammenfassung:	An obese 49-year-old man with no medical history of note presented in August, 2014, with a 5-week history of bloody diarrhoea, anorexia, and unintentional weight loss. He reported passing 20 bloody stools per day, with nocturnal disturbance, and on admission had pyrexia, tachycardia, anaemia, and a robust inflammatory response. Flexible sigmoidoscopy showed severe confluent colitis, and histopathology confirmed a first presentation of active ulcerative colitis.
ISSN:	0140-6736 1474-547X
DOI:	10.1016/S0140-6736(16)30857-1