Cooperative binding of the outer arm-docking complex underlies the regular arrangement of outer arm dynein in the axoneme

Outer arm dynein (OAD) in cilia and flagella is bound to the outer doublet microtubules every 24 nm. Periodic binding of OADs at specific sites is important for efficient cilia/flagella beating; however, the molecular mechanism that specifies OAD arrangement remains elusive. Studies using the green...

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Veröffentlicht in:Proceedings of the National Academy of Sciences - PNAS 2014-07, Vol.111 (26), p.9461-9466
Hauptverfasser: Owa, Mikito, Furuta, Akane, Usukura, Jiro, Arisaka, Fumio, King, Stephen M., Witman, George B., Kamiya, Ritsu, Wakabayashi, Ken-ichi
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Sprache:eng
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