Long-term surveillance is necessary after operative resection for intraductal papillary mucinous neoplasm of the pancreas

Background There is not enough evidence to establish an appropriate surveillance strategy after operative resection for intraductal papillary mucinous neoplasm. Methods This study included 257 consecutive intraductal papillary mucinous neoplasm patients who underwent operative resection between July...

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Veröffentlicht in:Surgery 2016-08, Vol.160 (2), p.306-317
Hauptverfasser: Hirono, Seiko, MD, Kawai, Manabu, MD, Okada, Ken-ichi, MD, Miyazawa, Motoki, MD, Shimizu, Atsushi, MD, Kitahata, Yuji, MD, Ueno, Masaki, MD, Yanagisawa, Akio, MD, Yamaue, Hiroki, MD
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Sprache:eng
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Zusammenfassung:Background There is not enough evidence to establish an appropriate surveillance strategy after operative resection for intraductal papillary mucinous neoplasm. Methods This study included 257 consecutive intraductal papillary mucinous neoplasm patients who underwent operative resection between July 1999 and March 2014. The frequencies, patterns, time-to-event, and risk factors for postoperative recurrence in intraductal papillary mucinous neoplasm were analyzed. Results Fifty-six intraductal papillary mucinous neoplasm patients (21.8%) had recurrence after the operation, including those with remnant pancreatic recurrence ( n  = 14) and extrapancreatic recurrence ( n  = 42). Remnant pancreatic recurrence had no influence on the overall survival, whereas patients with extrapancreatic recurrence had significantly worse overall survival ( P  
ISSN:0039-6060
1532-7361
DOI:10.1016/j.surg.2016.04.007