Isolated CMV infection causing perianal and sacral ulceration in a patient with aids

Isolated CMV infection causing perianal and sacral ulceration in a patient with aids

Cytomegalovirus (CMV) is a DNA virus estimated to infect 70-90% of the world’s population, producing minimal symptoms in immunocompetent hosts. In the immunocompromised host, CMV infection can be potentially fatal, producing systemic or localized forms. We report the case of a 52-year-old female wit...

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Veröffentlicht in:Journal of biological regulators and homeostatic agents 2016-04, Vol.30 (2 Suppl 2), p.13-15
Hauptverfasser: Klug, D J, Darling, M D, Kaley, J R, Tchernev, G, Chokoeva, A A, Wollina, U, Lotti, T, Fioranelli, M, Roccia, M G, Maximov, G K, Gagnon, A L, Patterson, J W
Format: Artikel
Sprache:eng
Schlagworte:
Acquired Immunodeficiency Syndrome - complications
Anal Canal - pathology
Cytomegalovirus Infections - complications
Cytomegalovirus Infections - pathology
Female
Humans
Middle Aged
Sacrum - pathology
Ulcer - pathology
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Zusammenfassung:Cytomegalovirus (CMV) is a DNA virus estimated to infect 70-90% of the world’s population, producing minimal symptoms in immunocompetent hosts. In the immunocompromised host, CMV infection can be potentially fatal, producing systemic or localized forms. We report the case of a 52-year-old female with acquired immunodeficiency virus (AIDS) who presented multiple sacral and perineal ulcers clinically and histopathologically consistent with CMV ulcerations. We discuss the patient’s clinical presentation and histologic findings to remind physicians to consider CMV as a cause for cutaneous and systemic infection in the immunocompromised host.
ISSN:0393-974X