Selective Recognition of Cysteine in Its Free and Protein-Bound States by the Zn super(2+) Complex of a Triazole-Based Calix[4]arene Conjugate

Selective Recognition of Cysteine in Its Free and Protein-Bound States by the Zn super(2+) Complex of a Triazole-Based Calix[4]arene Conjugate

Zinc-ed in: A highly fluorescent zinc complex of triazole-linked calix[4]arene (see scheme), [ZnL], for the selective recognition of Cys and other protein-bound/free thiols in the blood-serum milieu by mimicking the Zn super(2+)-induced redox switch has been developed.

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Veröffentlicht in:Chemistry : a European journal 2011-12, Vol.17 (50), p.13999-14003
Hauptverfasser: KumarPathak, Rakesh, Tabbasum, Khatija, KumarHinge, Vijaya, PullaRao, Chebrolu
Format: Artikel
Sprache:eng
Schlagworte:
Conjugates
Cysteine
Fluorescence
Recognition
Switches
Thiols
Zinc
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Beschreibung
Zusammenfassung:Zinc-ed in: A highly fluorescent zinc complex of triazole-linked calix[4]arene (see scheme), [ZnL], for the selective recognition of Cys and other protein-bound/free thiols in the blood-serum milieu by mimicking the Zn super(2+)-induced redox switch has been developed.
ISSN:0947-6539
1521-3765
DOI:10.1002/chem.201102791