Surface engineering of macrophages with nucleic acid aptamers for the capture of circulating tumor cells
In order to enhance the interactions between macrophages and cancer cells, thiol-terminated nucleic acid aptamers were immobilized on methacryloyl-functionalised carbohydrates of macrophages. The adhesion of cancer cells on the surface modified macrophages was significantly accelerated.
Gespeichert in:
| Veröffentlicht in: | Chemical communications (Cambridge, England) England), 2015-01, Vol.51 (98), p.17428-17430 |
|---|---|
| Hauptverfasser: | , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 17430 |
|---|---|
| container_issue | 98 |
| container_start_page | 17428 |
| container_title | Chemical communications (Cambridge, England) |
| container_volume | 51 |
| creator | Sugimoto, Shunsuke Moriyama, Rui Mori, Takeshi Iwasaki, Yasuhiko |
| description | In order to enhance the interactions between macrophages and cancer cells, thiol-terminated nucleic acid aptamers were immobilized on methacryloyl-functionalised carbohydrates of macrophages. The adhesion of cancer cells on the surface modified macrophages was significantly accelerated. |
| doi_str_mv | 10.1039/c5cc06211j |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_1800476013</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>1800476013</sourcerecordid><originalsourceid>FETCH-LOGICAL-c353t-1eed629839f00893e1465a0332fec3facbe7fac3ed3eb0e2cecf3de92db432bd3</originalsourceid><addsrcrecordid>eNqNkU1LxDAQhoMo7rp68QdIjiJUk06atEcpfrLgQQVvJU2n2y79WJMW8d-buqtXncPMMDzzMsxLyClnl5xBcmUiY5gMOV_vkTkHKYJIxG_7Ux8lgQIRzciRc2vmg0fxIZmFUshYJHJOqufRltogxW5Vd4i27la0L2mrje03lV6hox_1UNFuNA3WhmpTF1RvBt2idbTsLR0qpMZPRovTpqmtGRs9TELD2HrAYNO4Y3JQ6sbhya4uyOvtzUt6Hyyf7h7S62VgIIIh4IiFDJMYkpKxOAHkQkaaAYQlGvCX5qh8BiwAc4ahQVNCgUlY5ALCvIAFOd_qbmz_PqIbsrZ20wW6w350GY8ZE0oyDn-jSkkfoNg_UFBCiUQpj15sUf9A5yyW2cbWrbafGWfZ5FeWRmn67dejh892umPeYvGL_hgEX8M3kfA</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>1737474977</pqid></control><display><type>article</type><title>Surface engineering of macrophages with nucleic acid aptamers for the capture of circulating tumor cells</title><source>MEDLINE</source><source>Royal Society Of Chemistry Journals 2008-</source><source>Alma/SFX Local Collection</source><creator>Sugimoto, Shunsuke ; Moriyama, Rui ; Mori, Takeshi ; Iwasaki, Yasuhiko</creator><creatorcontrib>Sugimoto, Shunsuke ; Moriyama, Rui ; Mori, Takeshi ; Iwasaki, Yasuhiko</creatorcontrib><description>In order to enhance the interactions between macrophages and cancer cells, thiol-terminated nucleic acid aptamers were immobilized on methacryloyl-functionalised carbohydrates of macrophages. The adhesion of cancer cells on the surface modified macrophages was significantly accelerated.</description><identifier>ISSN: 1359-7345</identifier><identifier>EISSN: 1364-548X</identifier><identifier>DOI: 10.1039/c5cc06211j</identifier><identifier>PMID: 26468496</identifier><language>eng</language><publisher>England</publisher><subject>Adhesion ; Amino Sugars - chemistry ; Amino Sugars - metabolism ; Animals ; Aptamers, Nucleotide - chemistry ; Aptamers, Nucleotide - radiation effects ; Cancer ; Carbohydrates ; Cell Adhesion ; Cell Engineering ; Cell Line, Tumor ; Circulating ; Cytological Techniques ; Fluorescent Dyes - chemistry ; Humans ; Immobilized Nucleic Acids - chemistry ; Immobilized Nucleic Acids - radiation effects ; Light ; Lymphocytes - pathology ; Macrophages ; Macrophages - chemistry ; Macrophages - physiology ; Mice ; N-Acetylneuraminic Acid - chemistry ; Neoplastic Cells, Circulating - pathology ; Nucleic acids ; Receptor Protein-Tyrosine Kinases - metabolism ; Surface Properties ; Tumors</subject><ispartof>Chemical communications (Cambridge, England), 2015-01, Vol.51 (98), p.17428-17430</ispartof><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c353t-1eed629839f00893e1465a0332fec3facbe7fac3ed3eb0e2cecf3de92db432bd3</citedby><cites>FETCH-LOGICAL-c353t-1eed629839f00893e1465a0332fec3facbe7fac3ed3eb0e2cecf3de92db432bd3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,27922,27923</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/26468496$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Sugimoto, Shunsuke</creatorcontrib><creatorcontrib>Moriyama, Rui</creatorcontrib><creatorcontrib>Mori, Takeshi</creatorcontrib><creatorcontrib>Iwasaki, Yasuhiko</creatorcontrib><title>Surface engineering of macrophages with nucleic acid aptamers for the capture of circulating tumor cells</title><title>Chemical communications (Cambridge, England)</title><addtitle>Chem Commun (Camb)</addtitle><description>In order to enhance the interactions between macrophages and cancer cells, thiol-terminated nucleic acid aptamers were immobilized on methacryloyl-functionalised carbohydrates of macrophages. The adhesion of cancer cells on the surface modified macrophages was significantly accelerated.</description><subject>Adhesion</subject><subject>Amino Sugars - chemistry</subject><subject>Amino Sugars - metabolism</subject><subject>Animals</subject><subject>Aptamers, Nucleotide - chemistry</subject><subject>Aptamers, Nucleotide - radiation effects</subject><subject>Cancer</subject><subject>Carbohydrates</subject><subject>Cell Adhesion</subject><subject>Cell Engineering</subject><subject>Cell Line, Tumor</subject><subject>Circulating</subject><subject>Cytological Techniques</subject><subject>Fluorescent Dyes - chemistry</subject><subject>Humans</subject><subject>Immobilized Nucleic Acids - chemistry</subject><subject>Immobilized Nucleic Acids - radiation effects</subject><subject>Light</subject><subject>Lymphocytes - pathology</subject><subject>Macrophages</subject><subject>Macrophages - chemistry</subject><subject>Macrophages - physiology</subject><subject>Mice</subject><subject>N-Acetylneuraminic Acid - chemistry</subject><subject>Neoplastic Cells, Circulating - pathology</subject><subject>Nucleic acids</subject><subject>Receptor Protein-Tyrosine Kinases - metabolism</subject><subject>Surface Properties</subject><subject>Tumors</subject><issn>1359-7345</issn><issn>1364-548X</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2015</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqNkU1LxDAQhoMo7rp68QdIjiJUk06atEcpfrLgQQVvJU2n2y79WJMW8d-buqtXncPMMDzzMsxLyClnl5xBcmUiY5gMOV_vkTkHKYJIxG_7Ux8lgQIRzciRc2vmg0fxIZmFUshYJHJOqufRltogxW5Vd4i27la0L2mrje03lV6hox_1UNFuNA3WhmpTF1RvBt2idbTsLR0qpMZPRovTpqmtGRs9TELD2HrAYNO4Y3JQ6sbhya4uyOvtzUt6Hyyf7h7S62VgIIIh4IiFDJMYkpKxOAHkQkaaAYQlGvCX5qh8BiwAc4ahQVNCgUlY5ALCvIAFOd_qbmz_PqIbsrZ20wW6w350GY8ZE0oyDn-jSkkfoNg_UFBCiUQpj15sUf9A5yyW2cbWrbafGWfZ5FeWRmn67dejh892umPeYvGL_hgEX8M3kfA</recordid><startdate>20150101</startdate><enddate>20150101</enddate><creator>Sugimoto, Shunsuke</creator><creator>Moriyama, Rui</creator><creator>Mori, Takeshi</creator><creator>Iwasaki, Yasuhiko</creator><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope><scope>7TM</scope><scope>7SR</scope><scope>7U5</scope><scope>8BQ</scope><scope>8FD</scope><scope>JG9</scope><scope>L7M</scope></search><sort><creationdate>20150101</creationdate><title>Surface engineering of macrophages with nucleic acid aptamers for the capture of circulating tumor cells</title><author>Sugimoto, Shunsuke ; Moriyama, Rui ; Mori, Takeshi ; Iwasaki, Yasuhiko</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c353t-1eed629839f00893e1465a0332fec3facbe7fac3ed3eb0e2cecf3de92db432bd3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2015</creationdate><topic>Adhesion</topic><topic>Amino Sugars - chemistry</topic><topic>Amino Sugars - metabolism</topic><topic>Animals</topic><topic>Aptamers, Nucleotide - chemistry</topic><topic>Aptamers, Nucleotide - radiation effects</topic><topic>Cancer</topic><topic>Carbohydrates</topic><topic>Cell Adhesion</topic><topic>Cell Engineering</topic><topic>Cell Line, Tumor</topic><topic>Circulating</topic><topic>Cytological Techniques</topic><topic>Fluorescent Dyes - chemistry</topic><topic>Humans</topic><topic>Immobilized Nucleic Acids - chemistry</topic><topic>Immobilized Nucleic Acids - radiation effects</topic><topic>Light</topic><topic>Lymphocytes - pathology</topic><topic>Macrophages</topic><topic>Macrophages - chemistry</topic><topic>Macrophages - physiology</topic><topic>Mice</topic><topic>N-Acetylneuraminic Acid - chemistry</topic><topic>Neoplastic Cells, Circulating - pathology</topic><topic>Nucleic acids</topic><topic>Receptor Protein-Tyrosine Kinases - metabolism</topic><topic>Surface Properties</topic><topic>Tumors</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Sugimoto, Shunsuke</creatorcontrib><creatorcontrib>Moriyama, Rui</creatorcontrib><creatorcontrib>Mori, Takeshi</creatorcontrib><creatorcontrib>Iwasaki, Yasuhiko</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><collection>Nucleic Acids Abstracts</collection><collection>Engineered Materials Abstracts</collection><collection>Solid State and Superconductivity Abstracts</collection><collection>METADEX</collection><collection>Technology Research Database</collection><collection>Materials Research Database</collection><collection>Advanced Technologies Database with Aerospace</collection><jtitle>Chemical communications (Cambridge, England)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Sugimoto, Shunsuke</au><au>Moriyama, Rui</au><au>Mori, Takeshi</au><au>Iwasaki, Yasuhiko</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Surface engineering of macrophages with nucleic acid aptamers for the capture of circulating tumor cells</atitle><jtitle>Chemical communications (Cambridge, England)</jtitle><addtitle>Chem Commun (Camb)</addtitle><date>2015-01-01</date><risdate>2015</risdate><volume>51</volume><issue>98</issue><spage>17428</spage><epage>17430</epage><pages>17428-17430</pages><issn>1359-7345</issn><eissn>1364-548X</eissn><abstract>In order to enhance the interactions between macrophages and cancer cells, thiol-terminated nucleic acid aptamers were immobilized on methacryloyl-functionalised carbohydrates of macrophages. The adhesion of cancer cells on the surface modified macrophages was significantly accelerated.</abstract><cop>England</cop><pmid>26468496</pmid><doi>10.1039/c5cc06211j</doi><tpages>3</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 1359-7345 |
| ispartof | Chemical communications (Cambridge, England), 2015-01, Vol.51 (98), p.17428-17430 |
| issn | 1359-7345 1364-548X |
| language | eng |
| recordid | cdi_proquest_miscellaneous_1800476013 |
| source | MEDLINE; Royal Society Of Chemistry Journals 2008-; Alma/SFX Local Collection |
| subjects | Adhesion Amino Sugars - chemistry Amino Sugars - metabolism Animals Aptamers, Nucleotide - chemistry Aptamers, Nucleotide - radiation effects Cancer Carbohydrates Cell Adhesion Cell Engineering Cell Line, Tumor Circulating Cytological Techniques Fluorescent Dyes - chemistry Humans Immobilized Nucleic Acids - chemistry Immobilized Nucleic Acids - radiation effects Light Lymphocytes - pathology Macrophages Macrophages - chemistry Macrophages - physiology Mice N-Acetylneuraminic Acid - chemistry Neoplastic Cells, Circulating - pathology Nucleic acids Receptor Protein-Tyrosine Kinases - metabolism Surface Properties Tumors |
| title | Surface engineering of macrophages with nucleic acid aptamers for the capture of circulating tumor cells |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-10T08%3A09%3A58IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Surface%20engineering%20of%20macrophages%20with%20nucleic%20acid%20aptamers%20for%20the%20capture%20of%20circulating%20tumor%20cells&rft.jtitle=Chemical%20communications%20(Cambridge,%20England)&rft.au=Sugimoto,%20Shunsuke&rft.date=2015-01-01&rft.volume=51&rft.issue=98&rft.spage=17428&rft.epage=17430&rft.pages=17428-17430&rft.issn=1359-7345&rft.eissn=1364-548X&rft_id=info:doi/10.1039/c5cc06211j&rft_dat=%3Cproquest_cross%3E1800476013%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=1737474977&rft_id=info:pmid/26468496&rfr_iscdi=true |