Efficient and synergetic DNA delivery with pyridinium amphiphiles-gold nanoparticle composite systems having different packing parameters
Mixtures of highly curved pyridinium-decorated Au nanoparticles and standard pyridinium cationic lipids efficiently and synergetically transfected DNA in vitro, while displaying an excellent cytotoxic profile.
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Veröffentlicht in: | Chemical communications (Cambridge, England) England), 2016-01, Vol.52 (1), p.60-63 |
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container_title | Chemical communications (Cambridge, England) |
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creator | Kizewski, Adrian Ilies, Marc A |
description | Mixtures of highly curved pyridinium-decorated Au nanoparticles and standard pyridinium cationic lipids efficiently and synergetically transfected DNA in vitro, while displaying an excellent cytotoxic profile. |
doi_str_mv | 10.1039/c5cc05760d |
format | Article |
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source | MEDLINE; Royal Society Of Chemistry Journals; Alma/SFX Local Collection |
subjects | Cationic Cell Line, Tumor Curved Deoxyribonucleic acid DNA - administration & dosage DNA - genetics Gold Gold - chemistry Humans Lipids Nanoparticles Nanoparticles - chemistry Nanostructure Pyridinium Compounds - chemistry Surface-Active Agents - chemistry Transfection |
title | Efficient and synergetic DNA delivery with pyridinium amphiphiles-gold nanoparticle composite systems having different packing parameters |
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