Nickel-catalyzed synthesis of (E)-olefins from benzylic alcohol derivatives and arylacetonitriles via C-O activation

Nickel-catalyzed synthesis of (E)-olefins from benzylic alcohol derivatives and arylacetonitriles via C-O activation

An efficient Ni-catalyzed synthesis of (E)-olefins using the readily available benzylic alcohol derivatives and arylacetonitriles is described. This transformation should proceed via a tandem process involving nickel-catalyzed cross coupling via C-O activation and subsequent stereoselective E2 elimi...

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Veröffentlicht in:Chemical communications (Cambridge, England) England), 2016-01, Vol.52 (10), p.2157-2160
Hauptverfasser: Xiao, Jing, Yang, Jia, Chen, Tieqiao, Han, Li-Biao
Format: Artikel
Sprache:eng
Schlagworte:
Activation
Alcohols
Cross coupling
Derivatives
Nickel
Synthesis
Transformations
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Zusammenfassung:An efficient Ni-catalyzed synthesis of (E)-olefins using the readily available benzylic alcohol derivatives and arylacetonitriles is described. This transformation should proceed via a tandem process involving nickel-catalyzed cross coupling via C-O activation and subsequent stereoselective E2 elimination.
ISSN:1359-7345
1364-548X
DOI:10.1039/c5cc10005d