A bioluminescent sensor for highly selective and sensitive detection of human carboxylesterase 1 in complex biological samples

A highly selective and sensitive bioluminescent sensor (DME) for human carboxylesterase 1 (hCE1) has been developed and well characterized. DME could be used for real-time monitoring of hCE1 activities in complex biological samples and for bio-imaging of endogenous hCE1 in living cells. A highly sel...

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Veröffentlicht in:Chemical communications (Cambridge, England) England), 2016-01, Vol.52 (15), p.3183-3186
Hauptverfasser: Wang, Dan-Dan, Jin, Qiang, Zou, Li-Wei, Hou, Jie, Lv, Xia, Lei, Wei, Cheng, Hai-Ling, Ge, Guang-Bo, Yang, Ling
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container_end_page 3186
container_issue 15
container_start_page 3183
container_title Chemical communications (Cambridge, England)
container_volume 52
creator Wang, Dan-Dan
Jin, Qiang
Zou, Li-Wei
Hou, Jie
Lv, Xia
Lei, Wei
Cheng, Hai-Ling
Ge, Guang-Bo
Yang, Ling
description A highly selective and sensitive bioluminescent sensor (DME) for human carboxylesterase 1 (hCE1) has been developed and well characterized. DME could be used for real-time monitoring of hCE1 activities in complex biological samples and for bio-imaging of endogenous hCE1 in living cells. A highly selective and sensitive bioluminescent sensor ( DME ) for real-time monitoring of human carboxylesterase 1 (hCE1) activities in complex biological samples and bio-imaging of endogenous hCE1 in living cells.
doi_str_mv 10.1039/c5cc09874b
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source MEDLINE; Royal Society Of Chemistry Journals 2008-; Alma/SFX Local Collection
subjects Biological
Carboxylic Ester Hydrolases - metabolism
Cells (biology)
Human
Limit of Detection
Luminescence
Monitoring
Real time
Sensors
title A bioluminescent sensor for highly selective and sensitive detection of human carboxylesterase 1 in complex biological samples
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