A bioluminescent sensor for highly selective and sensitive detection of human carboxylesterase 1 in complex biological samples

A highly selective and sensitive bioluminescent sensor (DME) for human carboxylesterase 1 (hCE1) has been developed and well characterized. DME could be used for real-time monitoring of hCE1 activities in complex biological samples and for bio-imaging of endogenous hCE1 in living cells. A highly sel...

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Veröffentlicht in:	Chemical communications (Cambridge, England) England), 2016-01, Vol.52 (15), p.3183-3186
Hauptverfasser:	Wang, Dan-Dan, Jin, Qiang, Zou, Li-Wei, Hou, Jie, Lv, Xia, Lei, Wei, Cheng, Hai-Ling, Ge, Guang-Bo, Yang, Ling
Format:	Artikel
Sprache:	eng
Schlagworte:	Biological Carboxylic Ester Hydrolases - metabolism Cells (biology) Human Limit of Detection Luminescence Monitoring Real time Sensors
Online-Zugang:	Volltext
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Beschreibung
Zusammenfassung:	A highly selective and sensitive bioluminescent sensor (DME) for human carboxylesterase 1 (hCE1) has been developed and well characterized. DME could be used for real-time monitoring of hCE1 activities in complex biological samples and for bio-imaging of endogenous hCE1 in living cells. A highly selective and sensitive bioluminescent sensor ( DME ) for real-time monitoring of human carboxylesterase 1 (hCE1) activities in complex biological samples and bio-imaging of endogenous hCE1 in living cells.
ISSN:	1359-7345 1364-548X
DOI:	10.1039/c5cc09874b