Luminescent Materials on the Basis of Yttrium Oxide and Yttrium Aluminum Garnet Used for Photodynamic Therapy

Finely-dispersed phosphors of Y2O3:Eu and Y3Al5O12:Eu have been synthesized with the help of Pechini method and the method of self-propagating high-temperature synthesis (SHS). During the synthesis of phosphors on the basis of Y2O3 carried out with Pechini method the size of crystallites increases with the enlargement of concentration of yttrium, but it decreases when the method of SHS is applied. The structure of phosphors on the basis of Y3Al5O12 (YAG) is strongly amorphized. This fact agrees with the data of XRD and with the prevalence of the band with λmax = 613 nm in the spectra of this phosphor. The enlargement of yttrium concentration in it promotes the amorphisation of yttrium aluminum garnet and the decrease of a crystal phase content. The sample of Y3Al5O12:Eu synthesized with Pechini method has the maximum intensity, while in conditions of excitement with “high-level” X-ray radiation which corresponds to the radiation of industrial medical X-ray apparatus, the phosphor of Y2O3:Eu synthesized with the help of SHS showed the largest intensity. Colloid solutions prepared with the use of the samples synthesized by SHS method revealed a higher steadiness and a lower disposition to the sedimentation process. The samples of Y2O3:Eu phosphor possessing the smallest size of particles and the highest intensity of X-ray luminescence are the most suitable for the creation of pharmacological drugs used for photodynamic therapy.