Serosal involvement in IgG4-related disease: report of two cases and review of the literature

IgG4-related disease (IgG4-RD) is a recently described entity characterized by lymphoplasmacytic infiltrates, usually mimicking tumors, affecting almost every organ or system. Nevertheless, serosal involvement has been rarely reported. In this article, we report two cases of IgG4-RD with serosal inv...

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Veröffentlicht in:	Rheumatology international 2016-07, Vol.36 (7), p.1033-1041
Hauptverfasser:	González-Moreno, Juan, Losada-López, Inés, Gállego-Lezaun, Cristina, García-Gasalla, Mercedes, Gómez Bellvert, Cristina, Ortego Centeno, Norberto
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Aged, 80 and over Autoimmune Diseases - diagnosis Autoimmune Diseases - drug therapy Autoimmune Diseases - immunology Biomarkers - blood Cases with a Message Drug Therapy, Combination Female Humans Immunoglobulin G - blood Immunosuppressive Agents - therapeutic use Male Medicine Medicine & Public Health Middle Aged Pericardial Effusion - diagnosis Pericardial Effusion - drug therapy Pericardial Effusion - immunology Pericardium - diagnostic imaging Pericardium - immunology Pleura - diagnostic imaging Pleura - immunology Pleural Effusion - diagnosis Pleural Effusion - drug therapy Pleural Effusion - immunology Rheumatology Tomography, X-Ray Computed Treatment Outcome
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Zusammenfassung:	IgG4-related disease (IgG4-RD) is a recently described entity characterized by lymphoplasmacytic infiltrates, usually mimicking tumors, affecting almost every organ or system. Nevertheless, serosal involvement has been rarely reported. In this article, we report two cases of IgG4-RD with serosal involvement and review the literature. Because of the varied clinical pictures found in our review, we suggest a new terminology for the description of IgG4-RD with serosal involvement.
ISSN:	0172-8172 1437-160X
DOI:	10.1007/s00296-016-3501-8