Guideline-Concordant Versus Discordant Antimicrobial Therapy in Patients With Community-Onset Complicated Intra-abdominal Infections

Overall IDSA/SIS intra-abdominal infection guideline compliance was not associated with improved outcomes; however, there was a longer time to active therapy (P=.024) and higher mortality (P=.077) if empiric therapy was too narrow per guidelines. These findings support the need for the implementatio...

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Veröffentlicht in:	Infection control and hospital epidemiology 2016-07, Vol.37 (7), p.855-858
Hauptverfasser:	Huang, Lori L., Van Schooneveld, Trevor C., Huang, Robert D., Olsen, Keith M., Rupp, Mark E., Gross, Alan E.
Format:	Artikel
Sprache:	eng
Schlagworte:	Abdomen Adult Aged Anti-Infective Agents - therapeutic use Clinical outcomes Community-Acquired Infections - drug therapy Community-Acquired Infections - microbiology Community-Acquired Infections - mortality Concise Communications Cross Infection - drug therapy Cross Infection - mortality Guideline Adherence - statistics & numerical data Humans Intensive care Intraabdominal Infections - drug therapy Intraabdominal Infections - microbiology Intraabdominal Infections - mortality Length of stay Middle Aged Mortality Nursing Patients Practice Guidelines as Topic Retrospective Studies Staphylococcus infections Treatment Outcome
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Zusammenfassung:	Overall IDSA/SIS intra-abdominal infection guideline compliance was not associated with improved outcomes; however, there was a longer time to active therapy (P=.024) and higher mortality (P=.077) if empiric therapy was too narrow per guidelines. These findings support the need for the implementation of customized institutional guidelines adapted from the IDSA/SIS guidelines. Infect Control Hosp Epidemiol 2016;37:855–858
ISSN:	0899-823X 1559-6834
DOI:	10.1017/ice.2016.64