The effects of α-tocopherol administration in chronically lead exposed workers

The effects of α-tocopherol administration in chronically lead exposed workers

Highlights • Supplementation with α-tocopherol resulted in a decreased blood lead level. • Effects of supplementation with α-tocopherol on oxidative damage markers were not satisfactory. • There is no reason to administer α-tocopherol as a prophylaxis of lead poisoning.

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Veröffentlicht in:Environmental toxicology and pharmacology 2016-04, Vol.43, p.175-181
Hauptverfasser: Kasperczyk, Sławomir, Dobrakowski, Michał, Kasperczyk, Aleksandra, Nogaj, Ewa, Boroń, Marta, Birkner, Ewa
Format: Artikel
Sprache:eng
Schlagworte:
Alfa-tocopherol
alpha-Tocopherol - pharmacology
Antioxidants
Antioxidants - pharmacology
Dietary Supplements
Emergency
Glutathione - metabolism
Humans
Lead poisoning
Lead Poisoning - drug therapy
Lipid peroxidation
Male
Malondialdehyde - blood
Occupational Exposure - statistics & numerical data
Oxidative stress
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Beschreibung
Zusammenfassung:Highlights • Supplementation with α-tocopherol resulted in a decreased blood lead level. • Effects of supplementation with α-tocopherol on oxidative damage markers were not satisfactory. • There is no reason to administer α-tocopherol as a prophylaxis of lead poisoning.
ISSN:1382-6689
1872-7077
DOI:10.1016/j.etap.2016.03.012