Parkinson's disease and thalamus: facts and fancy

Parkinson's disease and thalamus: facts and fancy

[...]they blocked the thalamostriatal projection by chemogenetics and optogenetics and reversed the imbalance between the direct and indirect pathways, successfully restoring normal behaviour in parkinsonian animals. [...]this new report revives interest in the role of the thalamus in Parkinson'...

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Veröffentlicht in:Lancet neurology 2016-06, Vol.15 (7), p.e2-e2
Hauptverfasser: Blesa, Javier, Trigo-Damas, Inés, Obeso, José A
Format: Artikel
Sprache:eng
Schlagworte:
Animals
Dopamine
Neurology
Neurons
Parkinson's disease
Rodents
Studies
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Beschreibung
Zusammenfassung:[...]they blocked the thalamostriatal projection by chemogenetics and optogenetics and reversed the imbalance between the direct and indirect pathways, successfully restoring normal behaviour in parkinsonian animals. [...]this new report revives interest in the role of the thalamus in Parkinson's disease using state-of-the-art methods.
ISSN:1474-4422
1474-4465
DOI:10.1016/S1474-4422(16)30048-5