Distinct mechanisms of the newborn innate immunity
Highlights • Newborn immune-protection depends mainly on passive transfer of Immunoglobulin G from mother. • The innate and adaptive immunity in newborns is relatively naïve. • The immune responses in newborns can be improved using additional co-stimulatory agents. • Newborns are biased against the...
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| Veröffentlicht in: | Immunology letters 2016-05, Vol.173, p.42-54 |
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| container_title | Immunology letters |
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| creator | Kumar, Kingsley Manoj S Bhat, B. Vishnu |
| description | Highlights • Newborn immune-protection depends mainly on passive transfer of Immunoglobulin G from mother. • The innate and adaptive immunity in newborns is relatively naïve. • The immune responses in newborns can be improved using additional co-stimulatory agents. • Newborns are biased against the production of pro-inflammatory cytokines. • Understanding the immunological mechanisms in a newborn could help improve protection against infections. |
| doi_str_mv | 10.1016/j.imlet.2016.03.009 |
| format | Article |
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| fulltext | fulltext |
| identifier | ISSN: 0165-2478 |
| ispartof | Immunology letters, 2016-05, Vol.173, p.42-54 |
| issn | 0165-2478 1879-0542 |
| language | eng |
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| source | MEDLINE; ScienceDirect Journals (5 years ago - present) |
| subjects | Adaptive Immunity Allergy and Immunology Animals Animals, Newborn Cytokines - metabolism Humans Immune response Immune Tolerance Immunity, Innate Immunity, Maternally-Acquired Immunoglobulin G - immunology Infant, Newborn Innate immunity Microbiome Newborns Pro-inflammatory cytokines |
| title | Distinct mechanisms of the newborn innate immunity |
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