Plasma exchange-centered artificial liver support system in hepatitis B virus-related acute-on- chronic liver failure： a nationwide prospective multicenter study in China

BACKGROUND： Plasma exchange （PE）-centered artificial liver support system reduced the high mortality rate of hepa titis B virus （HBV）-related acute-on-chronic liver failure （ACLF）. But the data were diverse in different medical centers. The present prospective nationwide study was to evaluate the ef...

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Veröffentlicht in:	Hepatobiliary & pancreatic diseases international 2016-06, Vol.15 (3), p.275-281
Hauptverfasser:	Chen, Jia-Jia, Huang, Jian-Rong, Yang, Qian, Xu, Xiao-Wei, Liu, Xiao-Li, Hao, Shao-Rui, Wang, Hui-Fen, Han, Tao, Zhang, Jing, Gan, Jian-He, Gao, Zhi-Liang, Wang, Yu-Ming, Lin, Shu-Mei, Xie, Qing, Pan, Chen, Li, Lan-Juan
Format:	Artikel
Sprache:	eng
Schlagworte:	acute-on-chronic liver failure Acute-On-Chronic Liver Failure - blood Acute-On-Chronic Liver Failure - mortality Acute-On-Chronic Liver Failure - therapy Acute-On-Chronic Liver Failure - virology Adolescent Adult Age Factors Aged artificial liver support Bilirubin - blood Biomarkers - blood Chi-Square Distribution China Creatinine - blood Endocrinology & Metabolism Female Gastroenterology and Hepatology Hepatitis B - complications Hepatitis B - diagnosis Hepatitis B - mortality Humans liver failure Liver, Artificial - adverse effects Logistic Models Male Middle Aged Multivariate Analysis plasma exchange Plasma Exchange - adverse effects Plasma Exchange - mortality Prospective Studies Prothrombin Time Risk Factors Severity of Illness Index Time Factors Treatment Outcome Young Adult 乙型肝炎病毒人工肝多中心急性支持系统置换血浆衰竭
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Beschreibung
Zusammenfassung:	BACKGROUND： Plasma exchange （PE）-centered artificial liver support system reduced the high mortality rate of hepa titis B virus （HBV）-related acute-on-chronic liver failure （ACLF）. But the data were diverse in different medical centers. The present prospective nationwide study was to evaluate the effects of PE on patients with HBV-ACLF at different stages.
ISSN:	1499-3872
DOI:	10.1016/S1499-3872(16)60084-X