Awaji Criteria Improves the Diagnostic Sensitivity in Amyotrophic Lateral Sclerosis: a Systematic Review Using Individual Patient Data

Awaji Criteria Improves the Diagnostic Sensitivity in Amyotrophic Lateral Sclerosis: a Systematic Review Using Individual Patient Data

Highlights • Individual patient data analysis disclosed a higher sensitivity of the Awaji criteria when compared with the revised El Escorial criteria. • Modification of Awaji criteria, to include a “possible” diagnostic category significantly enhanced the diagnosis of ALS, particularly in limb onse...

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Veröffentlicht in:Clinical neurophysiology 2016-07, Vol.127 (7), p.2684-2691
Hauptverfasser: Geevasinga, Nimeshan, Loy, Clement T, Menon, Parvathi, de Carvalho, Mamede, Swash, Michael, Schrooten, Maarten, Van Damme, Philip, Gawel, Malgorzata, Sonoo, Masahiro, Higashihara, Mana, Noto, Yu-ichi, Kuwabara, Satoshi, Kiernan, Matthew C, Macaskill, Petra, Vucic, Steve
Format: Artikel
Sprache:eng
Schlagworte:
Adult
Aged
Aged, 80 and over
Amyotrophic lateral sclerosis
Amyotrophic Lateral Sclerosis - diagnosis
Awaji criteria
Case-Control Studies
El Escorial criteria
Female
Humans
Male
Meta-analysis
Middle Aged
Neurologic Examination - methods
Neurologic Examination - standards
Neurology
Sensitivity and Specificity
Severity of Illness Index
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Beschreibung
Zusammenfassung:Highlights • Individual patient data analysis disclosed a higher sensitivity of the Awaji criteria when compared with the revised El Escorial criteria. • Modification of Awaji criteria, to include a “possible” diagnostic category significantly enhanced the diagnosis of ALS, particularly in limb onset disease. • Disease duration exerted a significant effect on the diagnostic utility of the Awaji criteria.
ISSN:1388-2457
1872-8952
DOI:10.1016/j.clinph.2016.04.005