Brain protection during cephalosomatic anastomosis

Brain protection during cephalosomatic anastomosis

Cephalosomatic anastomosis requires neuroprotective techniques, such as deep hypothermia, to preserve brain activity. Despite the failure of pharmacologic neuroprotection, new strategies, including ischemic pre- and postconitioning and the use of Perftoran, have to be explored to complement hypother...

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Veröffentlicht in:Surgery 2016-07, Vol.160 (1), p.5-10
Hauptverfasser: Ren, XiaoPing, MD, Orlova, Elena V., PhD, Maevsky, Eugene I., PhD, Bonicalzi, Vincenzo, MD, Canavero, Sergio, MD
Format: Artikel
Sprache:eng
Schlagworte:
Animals
Brain - blood supply
Brain Tissue Transplantation - methods
Fluorocarbons - therapeutic use
Humans
Hypothermia, Induced
Ischemic Preconditioning
Neuroprotective Agents - therapeutic use
Surgery
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Zusammenfassung:Cephalosomatic anastomosis requires neuroprotective techniques, such as deep hypothermia, to preserve brain activity. Despite the failure of pharmacologic neuroprotection, new strategies, including ischemic pre- and postconitioning and the use of Perftoran, have to be explored to complement hypothermia. This article summarizes the field of brain protection during CSA and these promising strategies.
ISSN:0039-6060
1532-7361
DOI:10.1016/j.surg.2016.01.026