The mesentery in Crohnʼs disease: friend or foe?
PURPOSE OF REVIEWThis article assesses the role of the mesentery in Crohnʼs disease. RECENT FINDINGSThe mesentery is centrally positioned both anatomically and physiologically. Overlapping mesenteric and submucosal mesenchymal contributions are important in the pathobiology of Crohnʼs disease. Mesen...
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| Veröffentlicht in: | Current opinion in gastroenterology 2016-07, Vol.32 (4), p.267-273 |
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| container_title | Current opinion in gastroenterology |
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| creator | Coffey, John Calvin O‘Leary, Donal Peter Kiernan, Miranda G Faul, Peter |
| description | PURPOSE OF REVIEWThis article assesses the role of the mesentery in Crohnʼs disease.
RECENT FINDINGSThe mesentery is centrally positioned both anatomically and physiologically. Overlapping mesenteric and submucosal mesenchymal contributions are important in the pathobiology of Crohnʼs disease. Mesenteric contributions explain the topographic distribution of Crohnʼs disease in general and mucosal disease in particular. Operative strategies that are mesenteric based (i.e. mesocolic excision) may reduce rates of postoperative recurrence.
SUMMARYThe net effect of mesenteric events in Crohnʼs disease is pathologic. This can be targeted by operative means.
VIDEO ABSTRACThttp://links.lww.com/COG/A18. |
| doi_str_mv | 10.1097/MOG.0000000000000280 |
| format | Article |
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RECENT FINDINGSThe mesentery is centrally positioned both anatomically and physiologically. Overlapping mesenteric and submucosal mesenchymal contributions are important in the pathobiology of Crohnʼs disease. Mesenteric contributions explain the topographic distribution of Crohnʼs disease in general and mucosal disease in particular. Operative strategies that are mesenteric based (i.e. mesocolic excision) may reduce rates of postoperative recurrence.
SUMMARYThe net effect of mesenteric events in Crohnʼs disease is pathologic. This can be targeted by operative means.
VIDEO ABSTRACThttp://links.lww.com/COG/A18.</description><identifier>ISSN: 0267-1379</identifier><identifier>EISSN: 1531-7056</identifier><identifier>DOI: 10.1097/MOG.0000000000000280</identifier><identifier>PMID: 27115218</identifier><language>eng</language><publisher>United States: Copyright Wolters Kluwer Health, Inc. All rights reserved</publisher><subject>Colonoscopy - methods ; Crohn Disease - pathology ; Crohn Disease - surgery ; Humans ; Mesentery - pathology ; Mesentery - surgery ; Postoperative Complications - prevention & control ; Recurrence ; Risk Factors ; Secondary Prevention</subject><ispartof>Current opinion in gastroenterology, 2016-07, Vol.32 (4), p.267-273</ispartof><rights>Copyright © 2016 Wolters Kluwer Health, Inc. All rights reserved.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><cites>FETCH-LOGICAL-c3050-363f61c3829e01da37ac3f67685d8466a0e4279471c6eb1da6930f14cebe12313</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,27923,27924</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/27115218$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Coffey, John Calvin</creatorcontrib><creatorcontrib>O‘Leary, Donal Peter</creatorcontrib><creatorcontrib>Kiernan, Miranda G</creatorcontrib><creatorcontrib>Faul, Peter</creatorcontrib><title>The mesentery in Crohnʼs disease: friend or foe?</title><title>Current opinion in gastroenterology</title><addtitle>Curr Opin Gastroenterol</addtitle><description>PURPOSE OF REVIEWThis article assesses the role of the mesentery in Crohnʼs disease.
RECENT FINDINGSThe mesentery is centrally positioned both anatomically and physiologically. Overlapping mesenteric and submucosal mesenchymal contributions are important in the pathobiology of Crohnʼs disease. Mesenteric contributions explain the topographic distribution of Crohnʼs disease in general and mucosal disease in particular. Operative strategies that are mesenteric based (i.e. mesocolic excision) may reduce rates of postoperative recurrence.
SUMMARYThe net effect of mesenteric events in Crohnʼs disease is pathologic. This can be targeted by operative means.
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RECENT FINDINGSThe mesentery is centrally positioned both anatomically and physiologically. Overlapping mesenteric and submucosal mesenchymal contributions are important in the pathobiology of Crohnʼs disease. Mesenteric contributions explain the topographic distribution of Crohnʼs disease in general and mucosal disease in particular. Operative strategies that are mesenteric based (i.e. mesocolic excision) may reduce rates of postoperative recurrence.
SUMMARYThe net effect of mesenteric events in Crohnʼs disease is pathologic. This can be targeted by operative means.
VIDEO ABSTRACThttp://links.lww.com/COG/A18.</abstract><cop>United States</cop><pub>Copyright Wolters Kluwer Health, Inc. All rights reserved</pub><pmid>27115218</pmid><doi>10.1097/MOG.0000000000000280</doi><tpages>7</tpages></addata></record> |
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| language | eng |
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| source | MEDLINE; Journals@Ovid Complete |
| subjects | Colonoscopy - methods Crohn Disease - pathology Crohn Disease - surgery Humans Mesentery - pathology Mesentery - surgery Postoperative Complications - prevention & control Recurrence Risk Factors Secondary Prevention |
| title | The mesentery in Crohnʼs disease: friend or foe? |
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