Further toxicity studies with antimycin, a fish eradicant

Further toxicological studies on antimycin (Fintrol) are presented. Previously reported acute toxicity studies indicated that antimycin has a very low toxicity for mammals and chronic toxicity did not reveal any deleterious effects. These additional studies were designated to determine whether antimycin-treated waters and antimycin-killed fish contained toxic degradation products. Antimycin-treated water was given to dogs and rats as the sole cource of drinking water and antimycin-killed fish were administered to dogs and rats as one-half of their diet. Both tests lasted 3 months. In both studies no toxic effects were noticed in the animal which drank the treated water or which ate fish killed by antimycin. A decrease in food consumption was observed in a few dogs and rats at the beginning of the test. It was not considered toxic manifestation but it was clearly the reaction of the animals to the bitter taste of the compd.