Cytokine Expression in Gingival and Intestinal Tissues of Patients with Periodontitis and Inflammatory Bowel Disease: An Exploratory Study

Highlights • Cytokine expression was compared in gingival and intestinal tissues;. • IL-17A, IL-17F, IL-22, IL-25, IL-33, IL-10 and INF-ɣ were higher in gingival tissue;. • Cytokine clustering pattern was different in gingival and intestinal tissues;. • Gingival cytokines were similar in Crohn’s dis...

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Veröffentlicht in:	Archives of oral biology 2016-06, Vol.66, p.141-146
Hauptverfasser:	Menegat, Juliana Santos Bittencourt, Lira-Junior, Ronaldo, Siqueira, Mariana Alves, Brito, Fernanda, Carvalho, Ana Teresa, Fischer, Ricardo Guimarães, Figueredo, Carlos Marcelo
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Advanced Basic Science Aged Biopsy Colitis, Ulcerative - immunology Colitis, Ulcerative - metabolism Crohn Disease - immunology Crohn Disease - metabolism Cross-Sectional Studies Cytokines Cytokines - biosynthesis Cytokines - metabolism Dentistry Female Gingiva Gingiva - immunology Gingiva - metabolism Humans Inflammatory bowel disease Inflammatory Bowel Diseases - complications Inflammatory Bowel Diseases - immunology Inflammatory Bowel Diseases - metabolism Interferon-gamma - biosynthesis Interferon-gamma - immunology Interleukins - biosynthesis Intestinal Mucosa - immunology Intestinal Mucosa - metabolism Male Middle Aged Periodontitis Periodontitis - complications Periodontitis - immunology Periodontitis - metabolism Tumor Necrosis Factor-alpha - biosynthesis Tumor Necrosis Factor-alpha - immunology
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Zusammenfassung:	Highlights • Cytokine expression was compared in gingival and intestinal tissues;. • IL-17A, IL-17F, IL-22, IL-25, IL-33, IL-10 and INF-ɣ were higher in gingival tissue;. • Cytokine clustering pattern was different in gingival and intestinal tissues;. • Gingival cytokines were similar in Crohn’s disease and Ulcerative Colitis patients.
ISSN:	0003-9969 1879-1506
DOI:	10.1016/j.archoralbio.2016.02.018