A systematic review and meta-analysis of the impact of Spirulina supplementation on plasma lipid concentrations

Summary Background & aims The impact of Spirulina supplementation on plasma lipid concentrations has not been conclusively studied. Therefore the aim of the meta-analysis was to assess the effect of Spirulina supplementation on plasma lipid concentrations. Methods We searched PubMed and Scopus (...

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Veröffentlicht in:	Clinical nutrition (Edinburgh, Scotland) Scotland), 2016-08, Vol.35 (4), p.842-851
Hauptverfasser:	Serban, Maria-Corina, Sahebkar, Amirhossein, Dragan, Simona, Stoichescu-Hogea, Gheorghe, Ursoniu, Sorin, Andrica, Florina, Banach, Maciej
Format:	Artikel
Sprache:	eng
Schlagworte:	Cholesterol, HDL - blood Cholesterol, LDL - blood Databases, Factual Dietary Supplements Gastroenterology and Hepatology HDL-cholesterol Humans LDL-cholesterol Lipid Meta-analysis Randomized Controlled Trials as Topic Spirulina Spirulina platensis Systematic review Triglycerides - blood
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Zusammenfassung:	Summary Background & aims The impact of Spirulina supplementation on plasma lipid concentrations has not been conclusively studied. Therefore the aim of the meta-analysis was to assess the effect of Spirulina supplementation on plasma lipid concentrations. Methods We searched PubMed and Scopus (up to July 03, 2015) to identify randomized controlled trials (RCTs) that investigate the effect Spirulina supplementation on plasma lipid concentrations. Meta-analysis and meta-regression were performed using random-effects models. Results Random-effect meta-analysis of data from 7 RCTs showed a significant effect of supplementation with spirulina in reducing plasma concentrations of total cholesterol (WMD: −46.76 mg/dL, 95% CI: −67.31 to −26.22, p
ISSN:	0261-5614 1532-1983
DOI:	10.1016/j.clnu.2015.09.007